10.7 Other R packages that can be used for methylation analysis

  • DSS beta-binomial models with empirical Bayes for moderating dispersion.
  • BSseq Regional differential methylation analysis using smoothing and linear-regression-based tests.
  • BiSeq Regional differential methylation analysis using beta-binomial models.
  • MethylSeekR: Methylome segmentation using HMM and cutoffs.
  • QuasR: Methylation aware alignment and methylation calling, as well as fastQC-like fastq raw data quality check features.